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Redefining Drug Discovery

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"Our Centre of Excellence for External Drug Discovery plays an important role in seeking out highly innovative and transformative science, and capturing a diversity of ideas and talents outside our organization. This is a key element of our strategy to externalize R&D." Moncef Slaoui, Chairman of R&D, GSK

At GlaxoSmithKline (GSK) a specialized R&D business unit is driving growth in external drug discovery to complement the late-stage GSK pipeline. The Center of Excellence for External Drug Discovery (CEEDD) builds and personally manages unique risk/reward-sharing drug discovery alliances with world class biotech companies. We work directly with these companies to bring programs from target to clinical proof of concept, at which stage GSK has options to license for full development and commercialization. As a small, multidisciplinary team, we share our alliance companies’ entrepreneurial spirit and agility, and complement their capabilities with broad expertise and access to big pharma resources to bring innovative new medicines to more patients more quickly.

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SEEDD News

11 Jun 2008 - EPIX Pharmaceuticals Initiates Second Trial in Phase 2b Program for Alzheimer's Disease
Three-Month Monotherapy Trial with PRX-03140 to Evaluate Impact on Cognitive Function
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5 Jun 2008 - EPIX Pharmaceuticals Achieves Milestone For Third Discovery Program in Collaboration with GlaxoSmithKline
Using its proprietary, integrated computational-medicinal chemistry approach to drug discovery, EPIX has identified three lead candidates to move forward into lead optimization in its third G-protein coupled receptor (GPCR) discovery program. Under the terms of its collaboration with GSK, EPIX is entitled to receive a milestone payment of $3 million for identifying three candidates in this program and an additional $2.5 million for its overall progress in all three of the discovery programs that are part of its collaboration with GSK.
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