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Redefining Drug Discovery
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"Our Centre of Excellence for External Drug Discovery plays an important role in seeking out highly innovative and transformative science, and capturing a diversity of ideas and talents outside our organization. This is a key element of our strategy to externalize R&D." Moncef Slaoui, Chairman of R&D, GSK

At GlaxoSmithKline (GSK) a specialized R&D business unit is driving growth in external drug discovery to complement the late-stage GSK pipeline. The Center of Excellence for External Drug Discovery (CEEDD) builds and personally manages unique risk/reward-sharing drug discovery alliances with world class biotech companies. We work directly with these companies to bring programs from target to clinical proof of concept, at which stage GSK has options to license for full development and commercialization. As a small, multidisciplinary team, we share our alliance companies’ entrepreneurial spirit and agility, and complement their capabilities with broad expertise and access to big pharma resources to bring innovative new medicines to more patients more quickly.

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GlaxoSmithKline - Do More, feel better, live longer

SEEDD News

23 Jun 2009 - GSK and Chroma form alliance to develop novel macrophage-targeted therapeutics
GlaxoSmithKline (LSE: GSK) and Chroma Therapeutics Limited, announced today a collaboration to
develop macrophage-targeted compounds using Chroma’s proprietary esterase-sensitive motif (ESM)
technology, which adds amino acid esters to compounds with the aim of targetting the compounds to
specific cells in the inflammatory disease process.
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16 Jun 2009 - ChemoCentryx's novel Crohn's drug passes first stage of Phase II/III trial
Initial results from a Phase II/III trial show that ChemoCentryx's novel lead compound Traficet-EN (CCX282-B), which is being co-developed with GlaxoSmithKline, demonstrates preliminary efficacy and good tolerability for patients with moderate to severe Crohn's disease. Traficet-EN is an oral antagonist of the CCR9 chemokine receptor.
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